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亚搏app申报2020年度国家自然科学基金组织器官区域免疫特性与疾病重大研究计划的通知

发布者: 科技处发布时间: 2019-07-03浏览次数: 124

GEXUEYUAN(BU、ZHONGXIN)、FUSHUYIYUAN:

ZHONGSHUHEWAIZHOUMIANYIQIGUAN(RUGUSUI、XIONGXIAN、LINBAJIE、PIZANGDENG)DEMIANYIXUETEXING,YURENTIZHONGYAOJIBINGGAOFAZUZHIQIGUAN(RUGANZANG、CHANGDAO、FEI、NAODENG)DEMIANYIXUETEXINGCUNZAIJIAODAQUBIE。ZHEIXIEZUZHIQIGUANYOUYUJUYOUDUTEDEJIEGOU、SHENGLIGONGNENGHEZUZHIWEIHUANJING,KENENGHANYOUTEDINGHUOZHEDUTEDEXIBAOYAQUNHEGONGNENGFENZI,CONGERXINGCHENGLEQUYUMIANYITEXING,QUYUMIANYITEXINGYUSUOZAIZUZHIQIGUANXIANGGUANDEZHONGDUOJIBINGDEFASHENGFAZHANKENENGJINMIXIANGGUAN。YOUYUDUIJIBINGGAOFAZUZHIQIGUANDEQUYUMIANYITEXINGYANJIUJIAOSHAO,DUIYUJITIMIANYIGONGNENGJIQISHENGLIBINGLIYIYISHANGQUEFAQUANMIANSHENRUDERENSHI,ZAIYIDINGCHENGDUSHANGYINGXIANGLEMIANYIYUJIBINGYANJIUYIJIJIBINGMIANYIFANGZHIDEFAZHAN。WEILESHENRUCHANSHIJIBINGDEMIANYIBINGLIJIZHI,TUIJINZHUANHUAYIXUEYANJIU,POQIEXUYAODUIZUZHIQIGUANDEQUYUMIANYITEXINGJINXINGJICHUXING、QIANYANXINGHEXITONGXINGDEXIANDAOYANJIU,YIJIESHIQUYUMIANYITEXINGYUZHONGDAJIBINGDENEIZAILIANXI,XUNZHAOXINDEMIANYIZHILIAOBADIAN、TICHUXINDEJIBINGMIANYIFANGZHICELVE。

本重大研究计划旨在将免疫学的重大基础研究(区域免疫特性)与国家的重大需求(重大疾病防治)结合起来。以“组织器官的区域免疫特性与疾病”研究为核心,通过与免疫器官比较,重点研究重要疾病高发组织器官(如肝脏、肠、肺、脑、肾、关节等)的区域免疫特性,阐述这些组织器官中特有免疫细胞亚群的基本性状,揭示区域免疫特性的基本属性,发现形成组织器官区域免疫特性的细胞调控网络和分子调控网络,深入研究相关疾病的病理生理机制,以揭示区域免疫特性与重大疾病的内在联系,寻找新的免疫治疗靶点与途径。

一、科学目标

本重大研究计划的总体科学目标: 通过与免疫器官比对,运用多学科交叉,创建并整合多种技术和方法,阐释重要疾病高发组织器官(如肝脏、肠道、肺、脑、肾、关节等)的区域免疫特性,并对相关疾病提出新解释和探索新的免疫干预策略。

二、核心科学问题

本重大研究计划的核心科学问题是了解重要疾病高发组织器官(如肝脏、肠、肺、脑、肾、关节等)的区域免疫基本属性、组织器官区域免疫特性的网络调控机制以及组织器官区域免疫特性在疾病发生发展中的作用机制。

三、2020年度重点资助研究方向

BENZHONGDAYANJIUJIHUAJINGGUOZHONGQIPINGGUHOUYIJINRUJICHENGJIEDUAN,BENNIANDUJIHUANIZIZHUDEJICHENGXIANGMUYANJIUFANGXIANGRUXIA。QINGZAIZAIQIANQIZIZHUHEDIAOYANDEJICHUSHANG,XUANZEXIALIEYANJIUFANGXIANGZHONGDELIANGGEHUOZHEDUOGE,MINGQUEMUBIAO,JIZHONGYOUSHILILIANG,LIANHEGONGGUAN,SHIXIANKUAYUEFAZHAN。

(YI)LIYONGBINGZHENGHEDUOZHONGJISHU(GELEIZUXUEDASHUJU、GEZHONGDANXIBAOJISHU、KESHIHUAXINJISHU、NAMIJISHU)HETESEPINGTAI(TESHUJIBINGDONGWUMOXING、RENYUANHUAXIAOSHU),SHENRUJIEXIZUZHIQIGUANQUYUMIANYITEXINGDEJIAOCHAYANJIU。

(ER)WEIRAOZHONGGUORENGAOFAZHONGDAJIBINGDEZUZHIQIGUANQUYUMIANYITEXINGYUGONGNENGKAIZHANDEJICHUYULINCHUANGJIEHEDEYANJIU,GULIJIYULINCHUANGYANJIUDEFAXIAN,SHENRUTANTAOJIBINGFASHENGFAZHANDEMIANYIXUEJIZHI。

(SAN)JIBINGDUOFAQIGUANZHIJIAN(LIRUFEI-CHANG、NAO-CHANG、GAN-PI)DEQUYUMIANYITEXINGDEJIAOHUZUOYONGHEGUANLIANYANJIU。

亚搏app(SI)YIZIZHUFAXIANDEZHONGYAOZUZHIQIGUANXINMIANYIXIBAOYAQUN、XINGONGNENGSHUXING、XINJIBINGJIZHIWEIJICHUDEYUANCHUANGXINGYANJIU。

四、2020年度资助计划

2020年度拟资助集成项目5项左右,直接费用资助强度约为180万元/项,资助期限为2年,集成项目申请书中研究期限应填写“2021年1月1日—2022年12月31日”。资助项目数和资助经费将根据申请情况和申请项目研究工作的实际需要而定。

五、申请要求及注意事项

(YI)SHENQINGTIAOJIAN。

BENZHONGDAYANJIUJIHUAXIANGMUSHENQINGRENYINGDANGJUBEIYIXIATIAOJIAN:

亚搏app1.JUYOUCHENGDANJICHUYANJIUKETIDEJINGLI;

亚搏app2.JUYOUGAOJIZHUANYEJISHUZHIWU(ZHICHENG)。

亚搏appZAIZHANBOSHIHOUYANJIURENYUAN、ZHENGZAIGONGDUYANJIUSHENGXUEWEIYIJIWUGONGZUODANWEIHUOZHESUOZAIDANWEIBUSHIYITUODANWEIDERENYUANBUDEZUOWEISHENQINGRENJINXINGSHENQING。

(ER)XIANXIANGSHENQINGGUIDING。

JUYOUGAOJIZHUANYEJISHUZHIWU(ZHICHENG)DERENYUAN,SHENQINGHUOCANYUSHENQINGBENCIFABUDEZHONGDAYANJIUJIHUAJICHENGXIANGMUBUXIANXIANG。

(SAN)SHENQINGZHUYISHIXIANG。

1.本重大研究计划项目申请采取无纸化申请,项目申请人须于2020年7月25日16时前在线提交申请书、所有附件、科研诚信承诺书扫描件(请在信息系统中下载模板,打印填写后由法定代表人亲笔签字、依托单位加盖公章),无须提供纸质材料,并联系科技处审核。

亚搏app2.XIANGMUSHENQINGSHUCAIYONGZAIXIANFANGSHIZHUANXIE。DUISHENQINGRENJUTIYAOQIURUXIA:

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(2)BENZHONGDAYANJIUJIHUAZHIZAIJINMIWEIRAOHEXINKEXUEWENTI,JIANGDUIDUOXUEKEXIANGGUANYANJIUJINXINGZHANLVEXINGDEFANGXIANGYINDAOHEYOUSHIZHENGHE,CHENGWEIYIGEXIANGMUJIQUN。SHENQINGRENYINGGENJUBENZHONGDAYANJIUJIHUANIJIEJUEDEJUTIKEXUEWENTIHEXIANGMUZHINANGONGBUDENIZIZHUYANJIUFANGXIANG,ZIXINGNIDINGXIANGMUMINGCHENG、KEXUEMUBIAO、YANJIUNEIRONG、JISHULUXIANHEXIANGYINGDEYANJIUJINGFEIDENG。

(3)SHENQINGRENDENGLUKEXUEJIJINWANGLUOXINXIXITONGhttp://isisn.nsfc.gov.cn/(YIXIAJIANCHENGXINXIXITONG;MEIYOUXITONGZHANGHAODESHENQINGRENQINGXIANGYITUODANWEIJIJINGUANLILIANXIRENSHENQINGKAIHU),ANZHAOZHUANXIETIGANGJIXIANGGUANYAOQIUZHUANXIESHENQINGSHU。

(4)SHENQINGSHUZHONGDEZIZHULEIBIEXUANZE“ZHONGDAYANJIUJIHUA”,YALEISHUOMINGXUANZE“JICHENGXIANGMU”,FUZHUSHUOMINGXUANZE“ZUZHIQIGUANQUYUMIANYITEXINGYUJIBING”,GENJUSHENQINGDEJUTIYANJIUNEIRONGXUANZEXIANGYINGDESHENQINGDAIMA,YISHANGXUANZEBUZHUNQUEHUOWEIXUANZEDEXIANGMUSHENQINGJIANGBUYUSHOULI。

集成项目的合作研究单位不得超过4个。

(5)SHENQINGRENYINGDANGANZHAOZHONGDAYANJIUJIHUASHENQINGSHUDEZHUANXIETIGANGZHUANXIESHENQINGSHU,ZAIZHAIYAODIYIJUYINGDANGZHUMINGSHENQINGNEIRONGDUIYINGDEBENZHINANZHONGDIANZIZHUYANJIUFANGXIANGZHONGQUEQIEDEYANJIUZHONGDIAN,TONGSHIZAI“LIXIANGYIJUYUYANJIUNEIRONG”BUFENLUNSHUYUXIANGMUZHINANZUIJIEJINDEKEXUEWENTIDEGUANXI,YIJIDUIJIEJUEHEXINKEXUEWENTIHEZHONGDAYANJIUJIHUAZONGTIMUBIAODEGONGXIAN。

SHENQINGSHUXUANTIYINGFUHEBENZHONGDAYANJIUJIHUADESHISHIYUANZE,JUYOUMINGQUEDEGUANJIANKEXUEWENTI。SHENQINGSHUDENEIRONGYINGMIAOZHUNHEXINKEXUEWENTI,TUCHUYOUXIANMUBIAO,QIANGDIAOCHUANGXINDIANYUQIANYANJICHUKEXUEWENTIDEYANJIU。

RUGUOSHENQINGRENYIJINGCHENGDANYUBENZHONGDAYANJIUJIHUAXIANGGUANDEQITAKEJIJIHUAXIANGMU,YINGDANGZAISHENQINGSHUZHENGWENDE“YANJIUJICHUYUGONGZUOTIAOJIAN”BUFENLUNSHUSHENQINGXIANGMUYUQITAXIANGGUANXIANGMUDEQUBIEYULIANXI,YINGBIMIANTONGYIYANJIUNEIRONGZAIBUTONGZIZHUJIGOUSHENQINGDEQINGKUANG。

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亚搏app(7)SHENQINGRENWANCHENGSHENQINGSHUZHUANXIEHOU,ZAIXIANTIJIAODIANZISHENQINGSHUJIFUJIANCAILIAO。SHENQINGCAILIAOZHONGSUOXUDEFUJIANCAILIAO(YOUGUANZHENGMINGXIN、TUIJIANXINHEQITATEBIESHUOMINGYAOQIUTIJIAODEZHIZHICAILIAOYUANJIAN),QUANBUYIDIANZISAOMIAOJIANSHANGCHUAN。

亚搏app (SI)QITAZHUYISHIXIANG。

 1.WEISHIXIANZHONGDAYANJIUJIHUAZONGTIKEXUEMUBIAOHEDUOXUEKEJICHENG,HUODEZIZHUDEXIANGMUFUZERENYINGDANGCHENGNUOZUNSHOUXIANGGUANSHUJUHEZILIAOGUANLIYUGONGXIANGDEGUIDING,XIANGMUZHIXINGGUOCHENGZHONGYINGGUANZHUYUBENZHONGDAYANJIUJIHUAQITAXIANGMUZHIJIANDEXIANGHUZHICHENGGUANXI。

亚搏app 2.WEIJIAQIANGXIANGMUDEXUESHUJIAOLIU,CUJINXIANGMUQUNDEXINGCHENGHEDUOXUEKEJIAOCHAYUJICHENG,BENZHONGDAYANJIUJIHUAJIANGMEINIANJUBAN1CIZIZHUXIANGMUDENIANDUXUESHUJIAOLIUHUI,BINGJIANGBUDINGQIDIZUZHIXIANGGUANLINGYUDEXUESHUYANTAOHUI。HUOZIZHUXIANGMUFUZERENYOUYIWUCANJIABENZHONGDAYANJIUJIHUAZHIDAOZHUANJIAZUHEGUANLIGONGZUOZUSUOZUZHIDESHANGSHUXUESHUJIAOLIUHUODONG,BINGRENZHENKAIZHANXUESHUJIAOLIU。

  咨询方式:  国家自然科学基金委员会医学科学部四处联系电话:

 (校内联系人: 孙老师;联系电话: 65882010

KEJICHU

2020NIAN7YUE3RI


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